Search results for "Severe toxicity"

showing 2 items of 2 documents

Ernährungsphysiologie erhitzter Fette: Langfristige Tierversuche

1974

Das Fette, die bei intensiver Beruhrung mit dem Luftsauerstoff langere Zeit auf hohere Temperaturen erhitzt worden sind, toxische Eigenschaften entwickeln, ist in vielen Laboratorien ubereinstimmend gezeigt worden. Je nach Schwere des Eingriffs reichen die bei Futterungsversuchen erhobenen Befunde von einer praktisch symptomenlosen Vertraglichkeit uber mehr oder minder schwere Wachstumsverzogerungen junger Tiere bis zu einer hohen Toxicitat wie starke Erhohung der Letalitatsrate und schweren anatomischen und histologischen Veranderungen der Organe. Fritierfette haben sich beim Einhalten der folgenden Bedingungen: Temperaturen nicht uber 180° C, Vermeiden jeder lokalen Uberhitzung durch einw…

GynecologyPremature deathmedicine.medical_specialtyGrowth retardationChemistrymedicineThree generationsMicrosomal enzymesSevere toxicityFette, Seifen, Anstrichmittel
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The use of three-dimensional oral mucosa cell cultures to assess the toxicity of soldered and welded wires

2007

The aim of the present study was to determine whether there is a difference in toxicity and loss of viability of three-dimensional (3D) reconstructed human oral epithelium (RHOE) cell cultures induced by point-welded (PW), laser-welded (LW), and silver-soldered (SiS) orthodontic wires. Three types of soldered stainless steel (SS) wires: PW, LW, and SiS were prepared ( n = 3) and subjected to multiple end-point analysis (MEA). Six pieces were cut from each wire. Each piece was placed on the triplicate cell cultures (RHOE model based on TR 146 cells). After 24 hours of topical exposure, the cell cultures were cut and stained with haematoxylin/eosin. Toxicity was assessed by evaluating the mor…

medicine.medical_specialty3D cell culturesOrthodontic wireEosinCell SurvivalEndpoint DeterminationChemistryMouth MucosatoxicityNegative controlOrthodonticsHaematoxylinSurgeryAndrologychemistry.chemical_compoundmedicine.anatomical_structureCell cultureToxicityOrthodontic WiresmedicineHumanscytotoxicityDental SolderingOral mucosaSevere toxicityThe European Journal of Orthodontics
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